Epidemiological evidence for the links between sleep, circadian rhythms and metabolism.

  title={Epidemiological evidence for the links between sleep, circadian rhythms and metabolism.},
  author={James E Gangwisch},
  journal={Obesity reviews : an official journal of the International Association for the Study of Obesity},
  volume={10 Suppl 2},
Epidemiological data reveal parallel trends of decreasing sleep duration and increases in metabolic disorders such as obesity, diabetes and hypertension. There is growing evidence that these trends are mechanistically related. The seasonal expression of the thrifty genotype provides a conceptual framework to connect circadian and circannual rhythms, sleep and metabolism. Experimental studies have shown sleep deprivation to decrease leptin, increase ghrelin, increase appetite, compromise insulin… CONTINUE READING
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