Epidemiological evaluation of cytogenetic biomarkers as potential surrogate end-points for cancer.

@article{Hagmar2004EpidemiologicalEO,
  title={Epidemiological evaluation of cytogenetic biomarkers as potential surrogate end-points for cancer.},
  author={Lars Hagmar and Ulf Str{\"o}mberg and H{\aa}kan Tinnerberg and Zoli Mikoczy},
  journal={IARC scientific publications},
  year={2004},
  volume={157},
  pages={207-15}
}
Various occupational exposures have been monitored by chromosomal aberrations, sister chromatid exchanges and micronuclei in peripheral blood lymphocytes. During the last decade, epidemiological studies have evaluated whether any of these markers foreshadows cancer risk. Results from Nordic, Italian and Czech cohorts support an approximately twofold cancer risk among subjects with high frequencies of chromosomal aberrations, but no such association was seen for any of the other biomarkers. The… CONTINUE READING
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