Epidemiologic studies of fatal and nonfatal cardiovascular disease and ETS exposure from spousal smoking.

  title={Epidemiologic studies of fatal and nonfatal cardiovascular disease and ETS exposure from spousal smoking.},
  author={Michael J. Thun and Jane Henley and Louis Apicella},
  journal={Environmental Health Perspectives},
  pages={841 - 846}
This article reviews the epidemiologic studies of the association of ischemic heart disease risk and environmental tobacco smoke (ETS) exposure from a spouse who smokes. Seventeen studies (nine cohort, eight case-control) comprising more than 485,000 lifelong nonsmokers and 7,345 coronary heart disease (CHD) events were included in a meta-analysis. Together, these studies include 36% more CHD events and 58% more study subjects than were available for review by the U. S. Occupational Safety and… 

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