Epidemiologic review of the calcium channel blocker drugs. An up-to-date perspective on the proposed hazards.

@article{Kizer2001EpidemiologicRO,
  title={Epidemiologic review of the calcium channel blocker drugs. An up-to-date perspective on the proposed hazards.},
  author={Jorge R Kizer and Stephen E. Kimmel},
  journal={Archives of internal medicine},
  year={2001},
  volume={161 9},
  pages={1145-58}
}
In the setting of soaring popularity, postmarketing studies of calcium channel blockers came to suggest an increase in a variety of major adverse end points. The evidence, however, was largely observational, and large-scale trials capable of addressing the concerns were wanting. Clinical trials now support the safety and efficacy of the long-acting dihydropyridines for patients with both uncomplicated and diabetic hypertension, although conventional therapies and, in the latter case… CONTINUE READING

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