Epidemiologic correlates of ovarian cortical inclusion cysts (CICs) support a dual precursor pathway to pelvic epithelial cancer.

@article{Folkins2009EpidemiologicCO,
  title={Epidemiologic correlates of ovarian cortical inclusion cysts (CICs) support a dual precursor pathway to pelvic epithelial cancer.},
  author={Ann K. Folkins and Aasia Saleemuddin and L. Anne Garrett and Judy E Garber and Michael G. Muto and Shelley S Tworoger and Christopher P Crum},
  journal={Gynecologic oncology},
  year={2009},
  volume={115 1},
  pages={
          108-111
        }
}
OBJECTIVE Many ovarian carcinomas are presumed to arise within ovarian cortical inclusion cysts (CICs). This study examined the frequency of ovarian CICs in relation to epidemiologic risk factors in women with BRCA1 and BRCA2 (BRCA+) mutations. METHODS BRCA+ women who underwent risk-reducing bilateral salpingo-oophorectomy were studied (n=74). Fifteen demographic variables (e.g., age at time of surgery, age at first birth, age at menopause, body mass index (BMI), gravidity) from a review of… CONTINUE READING
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