Epidemiologic and evolutionary relationships between Romanian and Brazilian HIV-subtype F strains.

  title={Epidemiologic and evolutionary relationships between Romanian and Brazilian HIV-subtype F strains.},
  author={Claudiu I. Bandea and Andr{\'e} Luis Correia Ramos and Danuta A. Pieniazek and Ruxandra Angela Pascu and Amilcar Tanuri and G. Schochetman and Mark A. Rayfield},
  journal={Emerging Infectious Diseases},
  pages={91 - 93}
The initial classification of HIV-1 viruses as Western or African strains has been replaced by phylogenetic subtyping that uses nucleotide sequence data. Eight distinct phylogenetic HIV-1 lineages or subtypes, A to H, have been defined (1). Considering that the rate of HIV-1 genome evolution is estimated at 0.5% to 1% per year and that the average genetic distance between the HIV-1 subtypes is approximately 20%, it is likely that these subtypes originated before the HIV-1 pandemic (1). The… CONTINUE READING

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