Epidemiologic Relationships Between A1C and All-Cause Mortality During a Median 3.4-Year Follow-up of Glycemic Treatment in the ACCORD Trial

@inproceedings{Riddle2010EpidemiologicRB,
  title={Epidemiologic Relationships Between A1C and All-Cause Mortality During a Median 3.4-Year Follow-up of Glycemic Treatment in the ACCORD Trial},
  author={Matthew C Riddle and Walter T. Ambrosius and David J. Brillon and John B Buse and Robert P. Byington and Robert M. Cohen and David C Goff and Saul N. Malozowski and Karen L. Margolis and Jeffrey Lynn Probstfield and Adrian M. Schnall and Elizabeth R. Seaquist},
  booktitle={Diabetes care},
  year={2010}
}
OBJECTIVE Randomized treatment comparing an intensive glycemic treatment strategy with a standard strategy in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial was ended early because of an unexpected excess of mortality in the intensive arm. As part of ongoing post hoc analyses of potential mechanisms for this finding, we explored whether on-treatment A1C itself had an independent relationship with mortality. RESEARCH DESIGN AND METHODS Participants with type 2 diabetes (n… CONTINUE READING
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