Epicardial perivascular adipose tissue as a therapeutic target in obesity-related coronary artery disease.

@article{Payne2012EpicardialPA,
  title={Epicardial perivascular adipose tissue as a therapeutic target in obesity-related coronary artery disease.},
  author={Gregory A. Payne and Meredith C. Kohr and Johnathan D. Tune},
  journal={British journal of pharmacology},
  year={2012},
  volume={165 3},
  pages={659-69}
}
UNLABELLED Adipose tissue is an active endocrine and paracrine organ that may influence the development of atherosclerosis and vascular disease. In the setting of obesity, adipose tissue produces a variety of inflammatory cytokines (or adipokines) that are known to modulate key mechanisms of atherogenesis. In particular, adipose tissue located on the surface of the heart surrounding large coronary arteries (i.e. epicardial perivascular adipose tissue) has been implicated in the pathogenesis of… CONTINUE READING
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