Epicardial adipose excision slows the progression of porcine coronary atherosclerosis

@inproceedings{McKenney2014EpicardialAE,
  title={Epicardial adipose excision slows the progression of porcine coronary atherosclerosis},
  author={Mikaela L. McKenney and Kyle A. Schultz and Jack B H Boyd and James P Byrd and Mouhamad A Alloosh and Shawn D. Teague and Arturo A. Arce-Esquivel and John Fain and M. Harold Laughlin and Harold S. Sacks and Michael S Sturek},
  booktitle={Journal of cardiothoracic surgery},
  year={2014}
}
BACKGROUND In humans there is a positive association between epicardial adipose tissue (EAT) volume and coronary atherosclerosis (CAD) burden. We tested the hypothesis that EAT contributes locally to CAD in a pig model. METHODS Ossabaw miniature swine (n=9) were fed an atherogenic diet for 6 months to produce CAD. A 15 mm length by 3-5 mm width coronary EAT (cEAT) resection was performed over the middle segment of the left anterior descending artery (LAD) 15 mm distal to the left main… CONTINUE READING