Ephs and ephrins keep pancreatic Beta cells connected.


How insulin-secreting beta cells of the pancreas communicate with each other is largely unknown. In this issue of Cell, Konstantinova et al. (2007) show that the signaling proteins EphA and ephrin-A modulate insulin secretion, providing fresh insights into the functional significance of the clustering of beta cells, which occurs in islets.


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@article{Kulkarni2007EphsAE, title={Ephs and ephrins keep pancreatic Beta cells connected.}, author={Rohit N. Kulkarni and C Ronald Kahn}, journal={Cell}, year={2007}, volume={129 2}, pages={241-3} }