EphrinB2 coordinates the formation of a morphological boundary and cell epithelialization during somite segmentation.

@article{Watanabe2009EphrinB2CT,
  title={EphrinB2 coordinates the formation of a morphological boundary and cell epithelialization during somite segmentation.},
  author={Tadayoshi Watanabe and Yuki Sato and Daisuke Saito and Ryosuke Tadokoro and Yoshiko Takahashi},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2009},
  volume={106 18},
  pages={7467-72}
}
During early morphogenesis, tissue segregation is often accompanied by changes in cell shape. To understand how such coordination is regulated, somitogenesis was used as a model. When a somite forms in the anterior end of the presomitic mesoderm, an intersomitic boundary (gap) emerges, and it is rapidly followed by cell epithelialization at this border. It has been known that the gap formation is regulated by intercellular signals. We here demonstrate that cMeso-1, the chicken homolog of mouse… CONTINUE READING

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