EphrinB1 is essential in T-cell-T-cell co-operation during T-cell activation.

@article{Yu2004EphrinB1IE,
  title={EphrinB1 is essential in T-cell-T-cell co-operation during T-cell activation.},
  author={Guang Sheng Yu and Hongyu Luo and Yulian Wu and Jiang-ping Wu},
  journal={The Journal of biological chemistry},
  year={2004},
  volume={279 53},
  pages={
          55531-9
        }
}
Eph kinases are the largest family of receptor tyrosine kinases, and their ligands are ephrins (EFNs), which are also cell surface molecules. We have very limited knowledge about the expression and function of these kinases and their ligands in the immune system. In this study we investigated the effect of EFNB1 on mouse T-cells. EFNB1 and the Eph kinases it interacts with (collectively called EFNB1 receptors (EFNB1R)) were expressed on T-cells, B cells, and monocytes/macrophages. Some T-cells… CONTINUE READING
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