EphrinB 2 signalling modulates the neural differentiation of human dental pulp stem cells

@inproceedings{Heng2018EphrinB2S,
  title={EphrinB 2 signalling modulates the neural differentiation of human dental pulp stem cells},
  author={Boon Chin Heng and Ting Gong and Xu Jianguang and Lee Wei Lim and Chengfei Zhang},
  year={2018}
}
Dental pulp stem cells (DPSCs) originate from the embryonic neural crest and have neurogenic potential. The present study investigated the roles of the forward and reverse EphrinB2 signalling pathways during DPSC neurogenesis. Treatment of DPSCs with recombinant EphrinB2-Fc protein over 7 days in a neural induction culture resulted in significant downregulation of the following neural markers: βIII-Tubulin, neural cell adhesion molecule (NCAM), nestin, neurogenin 2 (NGN2), neurofilament medium… CONTINUE READING

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