Ephrin stimulation modulates T cell chemotaxis.

  title={Ephrin stimulation modulates T cell chemotaxis.},
  author={Nigel Sharfe and Andrew Freywald and Ana Toro and Harjit K Dadi and Chaim M. Roifman},
  journal={European journal of immunology},
  volume={32 12},
Eph receptor tyrosine kinases and their ligands, the ephrins, are known to play an important role in regulating cell migration and targeting in neuronal and endothelial cells. Recently, it has been shown that lymphoid cells also express Eph receptors, raising the possibility that Eph receptors may similarly regulate lymphocyte migration. Chemotaxis in response to soluble chemokine factors is an essential facet of T cell biology. We demonstrate here that T cell chemotaxis in response to both the… CONTINUE READING


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