Ephrin-B2 Controls Cell Motility and Adhesion during Blood-Vessel-Wall Assembly

@article{Foo2006EphrinB2CC,
  title={Ephrin-B2 Controls Cell Motility and Adhesion during Blood-Vessel-Wall Assembly},
  author={Shane Siang Chin Foo and Christopher J. Turner and Susanne Adams and Amelia Compagni and Deborah Aubyn and Naoko Kogata and Per Lindblom and Moshe Shani and Daniel Zicha and Ralf H Adams},
  journal={Cell},
  year={2006},
  volume={124},
  pages={161-173}
}
New blood vessels are initially formed through the assembly or sprouting of endothelial cells, but the recruitment of supporting pericytes and vascular smooth muscle cells (mural cells) ensures the formation of a mature and stable vascular network. Defective mural-cell coverage is associated with the poorly organized and leaky vasculature seen in tumors or other human diseases. Here we report that mural cells require ephrin-B2, a ligand for Eph receptor tyrosine kinases, for normal association… CONTINUE READING
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References

Publications referenced by this paper.
Showing 1-10 of 46 references

Abnormalities in pericytes on blood vessels and endothelial sprouts in tumors.

The American journal of pathology • 2002
View 4 Excerpts
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Cell adhesion to ephrinb2 is induced by EphB4 independently of its kinase activity.

Biochemical and biophysical research communications • 2004
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