Ephedrinium-based protic chiral ionic liquids for enantiomeric recognition.

@article{Rooy2011EphedriniumbasedPC,
  title={Ephedrinium-based protic chiral ionic liquids for enantiomeric recognition.},
  author={Sergio L de Rooy and Min Li and David K. Bwambok and Bilal El-Zahab and Santhosh K Challa and Isiah M Warner},
  journal={Chirality},
  year={2011},
  volume={23 1},
  pages={
          54-62
        }
}
We report the synthesis of a series of novel structurally related protic chiral ionic liquids (PCILs) derived from ephedrines. Enantiopure norephedrine, ephedrine, and methylephedrine were neutralized by use of fluorinated acids, bis(trifluoromethanesulfonyl)imide, and bis(pentafluoroethanesulfonyl)imide to afford six PCILs with protonated primary, secondary, and tertiary amines. The goal of this study is to investigate the influence of structure on both chiral recognition abilities and… CONTINUE READING