EphA4 constitutes a population-specific guidance cue for motor neurons.

  title={EphA4 constitutes a population-specific guidance cue for motor neurons.},
  author={Johann Eberhart and Mary E Swartz and Simon Andrea Koblar and Elena B Pasquale and Catherine Ellen Krull},
  journal={Developmental biology},
  volume={247 1},
Motor neurons in the ventral neural tube project axons specifically to their target muscles in the periphery. Although many of the transcription factors that specify motor neuron cell fates have been characterized, less is understood about the mechanisms that guide motor axons to their correct targets. We show that ectopic expression of EphA4 receptor tyrosine kinase alters the trajectories of a specific population of motor axons in the avian hindlimb. Most motor neurons in the medial portion… CONTINUE READING
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A role for the EphA family in the topographic targeting of vomeronasal axons

  • B. Knoll, K. Zarbalia, W. Wurst, U. Drescher
  • Development
  • 2001
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