EphA2-derived peptide vaccine with amphiphilic poly(γ-glutamic acid) nanoparticles elicits an anti-tumor effect against mouse liver tumor

@article{Yamaguchi2009EphA2derivedPV,
  title={EphA2-derived peptide vaccine with amphiphilic poly(γ-glutamic acid) nanoparticles elicits an anti-tumor effect against mouse liver tumor},
  author={Shinjiro Yamaguchi and Tomohide Tatsumi and Tetsuo Takehara and Akira Sasakawa and Masashi Yamamoto and Keisuke Kohga and T. Esashi Miyagi and Tatsuya Kanto and Naoki Hiramastu and Takami Akagi and Mitsuru Akashi and Norio Hayashi},
  journal={Cancer Immunology, Immunotherapy},
  year={2009},
  volume={59},
  pages={759-767}
}
The prognosis of liver cancer remains poor, but recent advances in nanotechnology offer promising possibilities for cancer treatment. Novel adjuvant, amphiphilic nanoparticles (NPs) composed of l-phenylalanine (Phe)-conjugated poly(γ-glutamic acid) (γ-PGA-Phe NPs) having excellent capacity for carrying peptides, were found to have the potential for use as a peptide vaccine against tumor models overexpressing artificial antigens, such as ovalbumin (OVA). However, the anti-tumor potential of… CONTINUE READING
13 Citations
46 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 13 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 46 references

Expression of the receptor tyrosine kinase EphA2 is increased in smokers and predicts poor survival in non-small cell lung cancer

  • JM Branan, W Dong, L Prudkin
  • Clin Cancer Res
  • 2009
1 Excerpt

Similar Papers

Loading similar papers…