Ependymal ciliary dysfunction and reactive astrocytosis in a reorganized subventricular zone after stroke.

@article{Young2013EpendymalCD,
  title={Ependymal ciliary dysfunction and reactive astrocytosis in a reorganized subventricular zone after stroke.},
  author={Christopher C Young and Judith M. van der Harg and Nicola J Lewis and Keith J Brooks and Alastair M Buchan and Francis G. Szele},
  journal={Cerebral cortex},
  year={2013},
  volume={23 3},
  pages={647-59}
}
Subventricular zone (SVZ) astrocytes and ependymal cells are both derived from radial glia and may have similar gliotic reactions after stroke. Diminishing SVZ neurogenesis worsens outcomes in mice, yet the effects of stroke on SVZ astrocytes and ependymal cells are poorly understood. We used mouse experimental stroke to determine if SVZ astrocytes and ependymal cells assume similar phenotypes and if stroke impacts their functions. Using lateral ventricular wall whole mount preparations, we… CONTINUE READING

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References

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Showing 1-10 of 74 references

A neurovascular niche for neurogenesis after stroke.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2006
View 4 Excerpts
Highly Influenced

Subventricular zone-mediated ependyma repair in the adult mammalian brain.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2008
View 5 Excerpts
Highly Influenced

Stroke induces ependymal cell transformation into radial glia in the subventricular zone of the adult rodent brain.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism • 2007
View 3 Excerpts
Highly Influenced

Adult ependymal cells are postmitotic and are derived from radial glial cells during embryogenesis.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2005
View 4 Excerpts
Highly Influenced

Proliferating subventricular zone cells in the adult mammalian forebrain can differentiate into neurons and glia.

Proceedings of the National Academy of Sciences of the United States of America • 1993
View 4 Excerpts
Highly Influenced

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