Eosinophils in the 1990s: new perspectives on their role in health and disease.

@article{Wardlaw1994EosinophilsIT,
  title={Eosinophils in the 1990s: new perspectives on their role in health and disease.},
  author={A J Wardlaw},
  journal={Postgraduate medical journal},
  year={1994},
  volume={70 826},
  pages={536-52}
}
  • A J Wardlaw
  • Published 1994 in Postgraduate medical journal
Eosinophils are characterized by their unique crystalloid granules that contain four basic proteins--MBP, ECP, EDN and EPO. The cell has many common features with neutrophils but, unlike that cell type, eosinophils utilize VLA-4/VCAM-1 as an adherence pathway and have a number of other receptors not shared by neutrophils. These include recognition units for IgE (distinct from CD23), and receptors for IL-5, IL-3 and RANTES. Following stimulation with a variety of agents, eosinophils… CONTINUE READING

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