Eosinophils act as antigen-presenting cells to induce immunity to Strongyloides stercoralis in mice.

@article{Padigel2007EosinophilsAA,
  title={Eosinophils act as antigen-presenting cells to induce immunity to Strongyloides stercoralis in mice.},
  author={Udaikumar M. Padigel and Jessica A. Hess and James Joseph Lee and James Barron Lok and Thomas J. Nolan and Gerhard A. Schad and David Abraham},
  journal={The Journal of infectious diseases},
  year={2007},
  volume={196 12},
  pages={
          1844-51
        }
}
The objective of the present study was to explore the ability of eosinophils to present Strongyloides stercoralis antigen in naive and immunized mice. Antigen-pulsed eosinophils were injected intraperitoneally into naive or immunized mice, and then mice were examined for antigen-specific immune responses. A single inoculation of antigen-pulsed eosinophils was sufficient to prime naive mice and to boost immunized mice for antigen-specific T helper cell type 2 (Th2) immune responses with… CONTINUE READING
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