Eosinophils: singularly destructive effector cells or purveyors of immunoregulation?

@article{Jacobsen2007EosinophilsSD,
  title={Eosinophils: singularly destructive effector cells or purveyors of immunoregulation?},
  author={Elizabeth A. Jacobsen and Anna G. Taranova and Nancy A. Lee and James Joseph Lee},
  journal={The Journal of allergy and clinical immunology},
  year={2007},
  volume={119 6},
  pages={
          1313-20
        }
}
Eosinophils are granulocytes typically associated with immune responses to a limited number of specific insults, including helminth infection and exposure to various allergens. Moreover, the overwhelming consensus from the literature is that eosinophils evolved as uniquely destructive leukocytes with cytotoxic activities as an adaptation for host defense. However, recent studies now suggest that the parochial caricature of eosinophils as effector cells with nonspecific killing abilities that… CONTINUE READING
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