Eosinophils, bronchial hyperreactivity and late-phase asthmatic reactions.

@article{Durham1985EosinophilsBH,
  title={Eosinophils, bronchial hyperreactivity and late-phase asthmatic reactions.},
  author={Stephen R. Durham and A Barry Kay},
  journal={Clinical allergy},
  year={1985},
  volume={15 5},
  pages={
          411-8
        }
}
We have measured airways reactivity (methacholine PC20) and blood eosinophils in eleven asthmatics with allergen-induced late-phase reactions. Before challenge there was a significant (P less than 0.05) inverse correlation between blood eosinophils and the methacholine PC20. After allergen inhalation eosinophil counts were significantly (P less than 0.01) elevated at 24 hr. These increases in blood eosinophil counts were not observed in patients who developed single early responses. The… CONTINUE READING
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