Eosinophilic Granulomatosis with Polyangiitis (Churg‐Strauss)
@article{Nguyen2018EosinophilicGW, title={Eosinophilic Granulomatosis with Polyangiitis (Churg‐Strauss)}, author={Yann Nguyen and Lo{\"i}c Guillevin}, journal={Seminars in Respiratory and Critical Care Medicine}, year={2018}, volume={39}, pages={471–481} }
&NA; Eosinophilic granulomatosis with polyangiitis (EGPA), formerly called Churg‐Strauss syndrome, is a systemic necrotizing vasculitis of small‐ and medium‐size vessels, characterized by asthma and blood eosinophilia. EGPA typically occurs in patients with preexisting asthma, and involves the skin, lungs, and peripheral nerves. Poor‐prognosis factors (i.e., involvement(s) of the gastrointestinal tract, heart, and/or kidney) have been assessed with the Five‐Factor Score (FFS). One‐third of the…
62 Citations
Eosinophilic Granulomatosis with Polyangiitis: Experiences in Korean Patients
- MedicineYonsei medical journal
- 2019
The classification criteria for EGPA is described and recommendations for the evaluation and management of EGPA with conventional and newly suggested drugs for EGpa are described.
Eosinophilic granulomatosis with polyangiitis: modern view on pathogenesis and treatment (literature review)
- MedicineModern pediatrics. Ukraine
- 2020
Clinical manifestations in EGPA tend to divide patients into two subset of the disease, with a predominance of vasculitic or eosinophilic manifestations, and ANCA can differentiate between these two subsets, but there is no insufficient understanding to use phenotype2tailored therapies.
Churg Strauss Syndrome
- Medicine
- 2020
Churg Straus Syndrome – renamed as eosinophilic granulomatosis with polyangiitis (EGPA) – is a specific variant of the group of diseases characterized by necrotizing vasculitis of small and…
Treatment of Eosinophilic Granulomatosis with Polyangiitis: A Review
- Medicine, BiologyDrugs
- 2018
Characteristics of eosinophilic granulomatosis with polyangiitis are reviewed and an overview of established and novel pharmacological agents is provided.
Eosinophilic granulomatosis with polyangiitis as a rare cause of the syndrome of inappropriate antidiuretic hormone secretion
- MedicineIrish Journal of Medical Science (1971 -)
- 2022
A rare case of syndrome of the inappropriate antidiuretic hormone (ADH) secretion (SIadH) secondary to EGPA is reported, which implies a causality between two conditions.
Mepolizumab for the treatment of eosinophilic granulomatosis with polyangiitis
- Medicine, PsychologyExpert opinion on biological therapy
- 2019
The available literature supports the use of mepolizumab for the induction and maintenance of remission of refractory, relapsing, or glucocorticoid-dependent EGPA with potentially greater benefit in those who are ANCA-positive or those with greater eosinophilia (150 cells/L).
Dividing the Janus vasculitis? Pathophysiology of eosinophilic granulomatosis with polyangitis.
- Medicine, BiologyAutoimmunity reviews
- 2016
Granulomatosis with polyangiitis presenting with pachymeningitis and persistent headache
- Medicine
- 2020
A case of granulomatosis with polyangiitis in a patient with persistent frontal headache, for a very long time considered as migraine versus tension-type headache is reported.
Respiratory manifestations of eosinophilic granulomatosis with polyangiitis (Churg–Strauss)
- MedicineEuropean Respiratory Journal
- 2016
In EGPA, asthma is severe, antedates systemic manifestations by a mean of 12 years, and progresses to long-term persistent airflow obstruction despite corticosteroids in a large proportion of patients, which affects long- term management and morbidity.
Granulomatosis eosinofílica con poliangitis: reporte de un caso y revisión de la literatura
- Medicine
- 2017
The case of a 13 year old boy with diffi cult to control asthma and impaired general condition, which was fi nally diagnosed with EGPA, ANCA-negative, is reported.
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