Eosinophilia-myalgia syndrome and tryptophan production: a cautionary tale.

@article{Mayeno1994EosinophiliamyalgiaSA,
  title={Eosinophilia-myalgia syndrome and tryptophan production: a cautionary tale.},
  author={A N Mayeno and Gerald J. Gleich},
  journal={Trends in biotechnology},
  year={1994},
  volume={12 9},
  pages={346-52}
}
An epidemic of a new disease, termed eosinophilia-myalgia syndrome, occurred in the USA in 1989. This syndrome was linked to the consumption of L-tryptophan manufactured by a single company utilizing a fermentation process. All the findings indicate that the illness was probably triggered by an impurity formed when the manufacturing conditions were modified… CONTINUE READING