Eosinophilia-myalgia syndrome among the non-L-tryptophan users and pre-epidemic cases.


OBJECTIVE Eosinophilia-myalgia syndrome (EMS) has been associated with L-tryptophan (LT) use since 1989, but as yet no etiologic agent has been identified. We describe the non-L-tryptophan associated cases of EMS, and those patients with illness onset preceding the 1989 epidemic. METHODS Review of all patients in the EMS national state based surveillance… (More)