Eosinophil peroxidase deficiency in New Zealand white mice.

Abstract

Eosinophil peroxidase (EPO) is one of the granule enzymes in the eosinophil-specific granules and is distinct from myeloperoxidase. Here we report that peroxidase activity was absent in eosinophils of New Zealand White (NZW) mice. When NZW, New Zealand Black and their F1 mice were treated with cyclophosphamide followed by Toxocara canis infection, the… (More)

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