Eosinophil granules function extracellularly as receptor-mediated secretory organelles.

@article{Neves2008EosinophilGF,
  title={Eosinophil granules function extracellularly as receptor-mediated secretory organelles.},
  author={Josiane Sabbadini Neves and Sandra Aurora Chavez Perez and Lisa A Spencer and Rossana C N Melo and Lauren E Reynolds and Ionita Ghiran and Salahaddin Mahmudi-Azer and Solomon Olawole Odemuyiwa and Ann M. Dvorak and Redwan Moqbel and Peter F. Weller},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2008},
  volume={105 47},
  pages={18478-83}
}
Intracellular granules in several types of leukocytes contain preformed proteins whose secretions contribute to immune and inflammatory functions of leukocytes, including eosinophils, cells notably associated with asthma, allergic inflammation, and helminthic infections. Cytokines and chemokines typically elicit extracellular secretion of granule proteins… CONTINUE READING