Eosinophil chemotactic activity in Leishmania amazonensis promastigotes

  title={Eosinophil chemotactic activity in Leishmania amazonensis promastigotes},
  author={Saburo Saito and A. Hamada and N. Watanabe and T. Obata and K. Katakura and H. Ohtomo},
  journal={Parasitology Research},
  • Saburo Saito, A. Hamada, +3 authors H. Ohtomo
  • Published 1996
  • Biology, Medicine
  • Parasitology Research
  • Abstract Tissue eosinophilia was observed in the subcutaneous tissue of mice shortly after their inoculation not only with living but also with lysed promastigotes of Leishmania amazonensis. Intraperitoneal inoculation of lysed promastigotes from five different Leishmania species (L. donovani, L. chagasi, L. tropica, L. amazonensis, and L. braziliensis) induced eosinophil accumulation in the mouse peritoneum. This eosinophil infiltration was also detected in C5-deficient AKR mice, indicating… CONTINUE READING
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