Eosinophil activity in bronchial asthma.

  title={Eosinophil activity in bronchial asthma.},
  author={Per Venge},
  journal={Allergy proceedings : the official journal of regional and state allergy societies},
  volume={15 3},
  • Per Venge
  • Published 1994 in
    Allergy proceedings : the official journal of…
Eosinophil cationic proteins (ECP), eosinophil protein X (EPX), eosinophil peroxidase (EPO), eosinophil-derived neurotoxin (EDN), and the major basic protein (MBP) have been identified as potent cytotoxic secretory proteins in degranulated eosinophils. Studies of these proteins have clearly indicated a role for eosinophil-derived proteins in inflammatory diseases, including asthmatic inflammation. It has been shown that higher levels of ECP in asthmatics were concomitant with severity of the… CONTINUE READING


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