Eosinophil Cationic Protein (ECP), a predictive marker of bullous pemphigoid severity and outcome

@inproceedings{Giusti2017EosinophilCP,
  title={Eosinophil Cationic Protein (ECP), a predictive marker of bullous pemphigoid severity and outcome},
  author={Delphine Giusti and Gr{\'e}gory Gatouillat and S{\'e}bastien Le Jan and Julie Pl{\'e}e and Philippe Bernard and Frank D Antonicelli and Bach Nga Pham},
  booktitle={Scientific Reports},
  year={2017}
}
Bullous Pemphigoid (BP) is an inflammatory rare autoimmune bullous dermatosis, which outcome cannot be predicted through clinical investigations. Eosinophils are the main immune infiltrated cells in BP. However, the release of Major Basic Protein (MBP), Eosinophil Derived Neurotoxin (EDN), and Eosinophil Cationic Protein (ECP) upon eosinophil activation has still not been evaluated with respect to BP development. MBP, EDN and ECP were measured by ELISA in serum (n = 61) and blister fluid (n… CONTINUE READING
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