Enzymology of retinoic acid biosynthesis and degradation.


All-trans-retinoic acid is a biologically active derivative of vitamin A that regulates numerous physiological processes. The concentration of retinoic acid in the cells is tightly regulated, but the exact mechanisms responsible for this regulation are not completely understood, largely because the enzymes involved in the biosynthesis of retinoic acid have… (More)
DOI: 10.1194/jlr.R037028


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