Enzymology of one-carbon metabolism in methanogenic pathways.

  title={Enzymology of one-carbon metabolism in methanogenic pathways.},
  author={James G. Ferry},
  journal={FEMS microbiology reviews},
  volume={23 1},
Methanoarchaea, the largest and most phylogenetically diverse group in the Archaea domain, have evolved energy-yielding pathways marked by one-carbon biochemistry featuring novel cofactors and enzymes. All of the pathways have in common the two-electron reduction of methyl-coenzyme M to methane catalyzed by methyl-coenzyme M reductase but deviate in the source of the methyl group transferred to coenzyme M. Most of the methane produced in nature derives from acetate in a pathway where the… CONTINUE READING
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