Enzymology of bacterial lysine biosynthesis.

  title={Enzymology of bacterial lysine biosynthesis.},
  author={Giovanna Scapin and John S Blanchard},
  journal={Advances in enzymology and related areas of molecular biology},
Bacteria have evolved three strategies for the synthesis of lysine from aspartate via formation of the intermediate diaminopimelate (DAP), a metabolite that is also involved in peptidoglycan formation. The objectives of this chapter are descriptions of mechanistic studies on the reactions catalyzed by dihydrodipicolinate synthase, dihydrodopicolinate reductase, tetrahydrodipicolinate N-succinyl-transferase, N-succinyl-L,L-DAP aminotransferase, N-succinyl-L,L-DAP desuccinylase, L,L-DAP epimerase… CONTINUE READING
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