Enzymes in the conversion of cholesterol into bile acids.

  title={Enzymes in the conversion of cholesterol into bile acids.},
  author={Maria Norlin and Kjell Wikvall},
  journal={Current molecular medicine},
  volume={7 2},
This article aims to give an overview on the characterization, properties and regulation of enzymes, particularly the cytochrome (CYP) P450 enzymes, in the formation of bile acids from cholesterol. Bile acids are biologically active molecules that promote absorption of dietary lipids in the intestine and stimulate biliary excretion of cholesterol. Bile acids and oxysterols, formed from cholesterol, act as ligands to nuclear receptors regulating the expression of important genes in cholesterol… CONTINUE READING
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