Enzyme therapy for management of coeliac disease.

  title={Enzyme therapy for management of coeliac disease.},
  author={Hugh J. Cornell and Finlay A. Macrae and Joy Melny and Catherine J Pizzey and Fiona Cook and Sandra Mason and Prithi S. Bhathal and Teodor Stelmasiak},
  journal={Scandinavian journal of gastroenterology},
  volume={40 11},
OBJECTIVE Enzyme therapy based on animal digestive extracts was investigated as a means of completely digesting toxic residues from gluten in the small intestine, thus providing a means of protection of the mucosa. MATERIAL AND METHODS A randomized, placebo-controlled, clinical trial of an encapsulated enzyme extract was conducted in 21 coeliac patients in remission who were challenged with a modest amount of gluten daily over 2 weeks. Enzyme extract (900 mg) in three divided doses was… CONTINUE READING
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