Enzyme profile of rat bile ductular epithelial cells in reference to the resistance phenotype in hepatocarcinogenesis.

@article{Mathis1989EnzymePO,
  title={Enzyme profile of rat bile ductular epithelial cells in reference to the resistance phenotype in hepatocarcinogenesis.},
  author={Georg A. Mathis and Sandra A. Walls and Paul M. D'Amico and Thomas F. Gengo and Alphonse E. Sirica},
  journal={Hepatology},
  year={1989},
  volume={9 3},
  pages={
          477-85
        }
}
An extensive bile ductular cell hyperplasia with the formation of well-differentiated bile ductules is the most prominent feature of rat liver at 6 to 15 weeks after bile duct ligation. We have improved our previous cell isolation procedure and are now routinely able to obtain from such livers high yields of viable bile ductular epithelial cells. These cells were characterized with respect to their specific activities of gamma-glutamyl transpeptidase and beta-glucuronidase and of select Phase I… CONTINUE READING

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  • International journal of experimental pathology
  • 1997
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References

Publications referenced by this paper.
SHOWING 1-10 OF 53 REFERENCES

Promotion of growth and 44~332-338

L Germain, M Noel, H Gourdeau
  • Cancer Res
  • 1989
VIEW 1 EXCERPT

I . et aI . Isolation and morphologic characterization of bile duct epithelial cells from rat liver t A b stract )

WL Richards, Y Tsukada
  • J Cell Biol
  • 1987

Senobiot . ic met . abolizing enzymes are not restricted to parenchymal cells in rat liver

Y Taira, JA Redick, Baron d
  • Mol Pharmacol
  • 1987

carcinogenesis in rats and the question of premalignancy

L Braun, Yaswen Goyette M
  • Adv Cancer Res
  • 1987