Enzyme-linked immunosorbent assay with conserved immunoreactive glycoproteins gp36 and gp19 has enhanced sensitivity and provides species-specific immunodiagnosis of Ehrlichia canis infection.

@article{Crdenas2007EnzymelinkedIA,
  title={Enzyme-linked immunosorbent assay with conserved immunoreactive glycoproteins gp36 and gp19 has enhanced sensitivity and provides species-specific immunodiagnosis of Ehrlichia canis infection.},
  author={Ana Mar{\'i}a C{\'a}rdenas and Carrie K Doyle and Xiaofeng Zhang and Kimberly A Nethery and Richard E Corstvet and David H Walker and Jere W McBride},
  journal={Clinical and vaccine immunology : CVI},
  year={2007},
  volume={14 2},
  pages={123-8}
}
Ehrlichia canis is the primary etiologic agent of canine monocytic ehrlichiosis, a globally distributed and potentially fatal disease of dogs. We previously reported on the identification of two conserved major immunoreactive antigens, gp36 and gp19, which are the first proteins to elicit an E. canis-specific antibody response, and gp200 and p28, which elicit strong antibody responses later in the acute phase of the infection. In this report, the sensitivities and specificities of five… CONTINUE READING
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