Enzyme-like acceleration for the hydrolysis of a DNA model promoted by a dinuclear Zn(II) catalyst in dilute aqueous ethanol.

@article{Liu2008EnzymelikeAF,
  title={Enzyme-like acceleration for the hydrolysis of a DNA model promoted by a dinuclear Zn(II) catalyst in dilute aqueous ethanol.},
  author={C. Liu and A. A. Neverov and R. Brown},
  journal={Journal of the American Chemical Society},
  year={2008},
  volume={130 42},
  pages={
          13870-2
        }
}
The rates and products of cleavage of methyl (2-chloro-4-nitrophenyl) phosphate (2) promoted by a dinuclear Zn(II) complex (3) of 1,3-bis-N,N'(1,5,9-triazacyclododecyl)propane along with 1 equiv of ethoxide were investigated in ethanol solution containing small amounts of water (8 mM <or= [H2O] <or= 2.1 M) at 25 degreesC and sspH 7.9. The kinetics of decomposition of 5 x 10(-5) M 2 in the presence of varying [3] (0.03 mM <or= [3] <or= 0.12 mM) in ethanol containing 28 mM water show very strong… Expand
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