Enzyme inhibition-based biosensor for the electrochemical detection of microcystins in natural blooms of cyanobacteria.

@article{Camps2007EnzymeIB,
  title={Enzyme inhibition-based biosensor for the electrochemical detection of microcystins in natural blooms of cyanobacteria.},
  author={M{\`o}nica Camp{\`a}s and Dorota Szydłowska and Marek Trojanowicz and Jean-Louis Marty},
  journal={Talanta},
  year={2007},
  volume={72 1},
  pages={179-86}
}
An electrochemical biosensor for the detection of microcystin has been developed based on the inhibition of the protein phosphatase 2A (PP2A) by this cyanobacterial toxin. The enzyme has been immobilised by entrapment using a poly(vinyl alcohol) azide-unit pendant water-soluble photopolymer (PVA-AWP). Electrode supports and immobilisation conditions have been optimised by colorimetric assays, the highest immobilisation yields being obtained with screen-printed graphite electrodes and the 1:2… CONTINUE READING

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