Enzyme induction following prenatale exposure to anticonvulsants measured by 13C-breath tests

Abstract

Enzyme activity for demethylation processes can be estimated in vivo non-invasively by 13C-breath tests (BT). After oral intake of stable isotope labeled 13C-aminopyrine (AP) (2 mg/kg) resp. 13C-methacetin (MAC) (1,5 mg/kg) 13CO2-concentration in breath samples measured by ratio mass-spectrometry will reflect cytochrom P450 dependent AP-N-demethylation resp… (More)
DOI: 10.1203/00006450-198408000-00080

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Cite this paper

@article{Rating1984EnzymeIF, title={Enzyme induction following prenatale exposure to anticonvulsants measured by 13C-breath tests}, author={Dr. P. Rating and H. E. Nau and Hans Helge}, journal={Pediatric Research}, year={1984}, volume={18}, pages={805-805} }