Enzyme immunoassay for 4-hydroxy-2-(4-methylphenyl)benzothiazole.

@article{Miyairi1993EnzymeIF,
  title={Enzyme immunoassay for 4-hydroxy-2-(4-methylphenyl)benzothiazole.},
  author={S. Miyairi and H. Shimada and H. Morita and N. Awata and J. Goto and T. Nambara},
  journal={Journal of pharmaceutical and biomedical analysis},
  year={1993},
  volume={11 6},
  pages={
          469-76
        }
}
  • S. Miyairi, H. Shimada, +3 authors T. Nambara
  • Published 1993
  • Chemistry, Medicine
  • Journal of pharmaceutical and biomedical analysis
  • A specific enzyme immunoassay (EIA) has been developed for 4-hydroxy-2-(4-methylphenyl)benzothiazole (KB-2714) (1), an active metabolite of 4-acetoxy-2-(4-methylphenyl)benzothiazole (KB-2683) (2) which is a promising anti-rheumatic agent. The EIA was based upon antiserum elicited against 5-(2-carboxyphenylazo)-4-hydroxy-2-(4-methylphenyl)benzothiazole (3)-bovine serum albumin conjugate and beta-galactosidase-labelled 5-amino-4-hydroxy-2-(4-methylphenyl)benzothiazole (5). The sensitivity of the… CONTINUE READING
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