Enzyme-free synthesis of natural phospholipids in water

  title={Enzyme-free synthesis of natural phospholipids in water},
  author={Luping Liu and Yaping Zou and Ahanjit Bhattacharya and Dingwa Zhang and Susan Q. Lang and Kendall N Houk and Neal K Devaraj},
All living organisms synthesize phospholipids as the primary constituent of their cell membranes. While phospholipids can spontaneously self-assemble in water to form membrane- bound vesicles, their aqueous synthesis requires pre-existing membrane-embedded enzymes. This limitation has led to models in which the first cells used simpler types of membrane building blocks and has hampered integration of phospholipid synthesis into artificial cells. Here we demonstrate that a combination of ion… CONTINUE READING