Enzyme activities in skeletal muscles from patients with peripheral arterial insufficiency.

@article{Bylund1976EnzymeAI,
  title={Enzyme activities in skeletal muscles from patients with peripheral arterial insufficiency.},
  author={A C Bylund and Jan Hammarsten and J. Holm and Tore Scherst{\'e}n},
  journal={European journal of clinical investigation},
  year={1976},
  volume={6 6},
  pages={
          425-9
        }
}
The enzyme pattern in gastrocnemius muscle tissue was studied in 39 patients with peripheral arterial insufficiency. Phosphofructokinase and glucose-6-phosphate-dehydrogenase were significantly increased in the skeletal muscles from these patients. The most pronounced changes were found in 3-OH-acyl-CoA-dehydrogenase, citrate synthase, and in cytochrome-c-oxidase. These enzyme activities were increased by 60, 40 and 25 per cent respectively. In patients with claudication as the only symptom… CONTINUE READING

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