Enzyme Patterns in Human Tissues. 3. Glycolytic Enzymes in Normal and Malignant Tissues of the Colon and Rectum.

@article{Shonk1965EnzymePI,
  title={Enzyme Patterns in Human Tissues. 3. Glycolytic Enzymes in Normal and Malignant Tissues of the Colon and Rectum.},
  author={C E Shonk and R N Arison and B J Koven and Hideyuki Majima and G E Boxer},
  journal={Cancer research},
  year={1965},
  volume={25},
  pages={206-13}
}
tissues form a rational basis for the development of new cancer chemotherapeutic agents. These differences have been primarily uncovered and studied in rodent tumors and it seems essential to validate or invalidate the extra polation from rodent to human tumors by similar studies in human tumors (16). Ever since Warburg (18) reported the observation of a high rate of aerobic glycolysis in most malignant tissues, interest in the study of the enzymes of the glycolytic pathway in tumors has… CONTINUE READING

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