Enzymatic stabilization of gelatin-based scaffolds.

  title={Enzymatic stabilization of gelatin-based scaffolds.},
  author={Emmett P Broderick and Damien M O'Halloran and Yury A. Rochev and Martin Griffin and Russell John Collighan and Abhay Pandit},
  journal={Journal of biomedical materials research. Part B, Applied biomaterials},
  volume={72 1},
The definitive goal of this research is to develop protein-based scaffolds for use in soft tissue regeneration, particularly in the field of dermal healing. The premise of this investigation was to characterize the mechanical properties of gelatin cross-linked with microbial transglutaminase (mTGase) and to investigate the cytocompatibility of mTGase cross-linked gelatin. Dynamic rheological analysis revealed a significant increase in the storage modulus and thermal stability of gelatin after… CONTINUE READING
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