Enzymatic regulation of calcium current in dialyzed and intact molluscan neurons.

@article{Eckert1986EnzymaticRO,
  title={Enzymatic regulation of calcium current in dialyzed and intact molluscan neurons.},
  author={Roger E. Eckert and John E. Chad and Daniel Kalman},
  journal={Journal de physiologie},
  year={1986},
  volume={81 4},
  pages={
          318-24
        }
}
Isolated neurons of Helix aspersa were dialyzed and voltage clamped under conditions that isolate the Ca current. The rapid time-dependent run-down, or washout, of Ca current could be slowed by addition of 1 mM EGTA to the dialysis solution. A more effective means of slowing washout was the use of agents that promote protein phosphorylation, such as cAMP, Mg-ATP and the catalytic subunit (CS) of cAMP-dependent protein kinase, along with leupeptin, a tripeptide inhibitor of proteases. In the… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-7 OF 7 CITATIONS

Harmaline attenuates voltage--sensitive Ca(2+) currents in neurons of the inferior olive.

  • Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques
  • 2012
VIEW 1 EXCERPT
CITES BACKGROUND