Enzymatic production of 2-amino-2,3-dimethylbutyramide by cyanide-resistant nitrile hydratase


A novel enzymatic route for the synthesis of 2-amino-2,3-dimethylbutyramide (ADBA), important intermediate of highly potent and broad-spectrum imidazolinone herbicides, from 2-amino-2,3-dimethylbutyronitrile (ADBN) was developed. Strain Rhodococcus boritolerans CCTCC M 208108 harboring nitrile hydratase (NHase) towards ADBN was screened through a… (More)
DOI: 10.1007/s10295-011-1008-6


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