Enzymatic evidence of impaired reperfusion in diabetic patients after thrombolytic therapy for acute myocardial infarction: a role for plasminogen activator inhibitor?

@article{Gray1993EnzymaticEO,
  title={Enzymatic evidence of impaired reperfusion in diabetic patients after thrombolytic therapy for acute myocardial infarction: a role for plasminogen activator inhibitor?},
  author={Rosaire P Gray and John S. Yudkin and Dixie L Patterson},
  journal={British heart journal},
  year={1993},
  volume={70 6},
  pages={530-6}
}
OBJECTIVE To compare the activity of plasminogen activator inhibitor (PAI-1) in diabetic and non-diabetic patients admitted with acute myocardial infarction and to determine whether PAI-1 activity influences reperfusion after thrombolytic therapy. DESIGN Prospective study of patients admitted with acute myocardial infarction. SETTING District general hospital. MAIN OUTCOME MEASURES Reperfusion assessed by time to peak release of creatine kinase-MB isoenzyme. RESULTS Baseline PAI-1… CONTINUE READING

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