Enzymatic degradation of adhesive-dentin interfaces produced by mild self-etch adhesives.

@article{Munck2010EnzymaticDO,
  title={Enzymatic degradation of adhesive-dentin interfaces produced by mild self-etch adhesives.},
  author={Jan de Munck and Atsushi Mine and P. E. Van den Steen and Kirsten L van Landuyt and Andr{\'e} Poitevin and Ghislain Opdenakker and Bart van Meerbeek},
  journal={European journal of oral sciences},
  year={2010},
  volume={118 5},
  pages={494-501}
}
Endogenous matrix metalloproteinases (MMPs) released by adhesive procedures may degrade collagen in the hybrid layer and so compromise the bonding effectiveness of etch-and-rinse adhesives. In this study, endogenous enzymatic degradation was evaluated for several simplified self-etch adhesives. In addition, primers were modified by adding two MMP inhibitors: chlorhexidine, a commonly used disinfectant, but also a non-specific MMP inhibitor; and SB-3CT, a specific inhibitor of MMP-2 and MMP-9… CONTINUE READING